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Educational library

Peptide library

Learn what they are, how they work, what has been researched and what to watch for. Educational information, with no recommendations or doses.

Metabolism and weight

6

Metabolism and weight
Tirzepatide

Metabolism and weight
Requires a professional evaluation
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What is it?
Tirzepatide is a synthetic dual-action peptide that acts as an agonist of the GLP-1 and GIP receptors, two incretin hormones that regulate appetite, metabolism and glucose control.

How does it work biologically?
Tirzepatide binds to and activates GLP-1 and GIP receptors in the body, mimicking the action of natural incretin hormones. This helps regulate appetite, improve insulin sensitivity and slow gastric emptying, supporting better control of weight and blood glucose.

Researched benefits

Support for body weight reduction.
Better blood glucose control.
Improved insulin sensitivity.
Possible cardiometabolic benefits in clinical studies.
Favorable effects on metabolic markers.
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation in people with a medical history, especially diabetes, gastrointestinal problems or endocrine conditions.
Dosing and duration should be personalized according to goals and professional supervision.
May not be suitable in certain cases (e.g. pregnancy, breastfeeding, history of pancreatitis or medullary thyroid cancer).

What to watch for during use

Lower appetite and a greater feeling of fullness.
Changes in digestive regularity (nausea, constipation or diarrhea are common at the beginning).
Gradual decrease in body weight.
Improvement in blood glucose levels and metabolic markers.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Metabolism and weight
Retatrutide

Triple GIP / GLP-1 / glucagon receptor agonist
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What is it?
Retatrutide is a synthetic peptide that acts as a triple agonist at the GIP, GLP-1 and glucagon receptors, three key metabolic pathways that regulate appetite, energy expenditure and glucose control. It is in advanced-stage clinical trials; its regulatory status varies by country.

How does it work biologically?
Retatrutide simultaneously activates GIP, GLP-1 and glucagon receptors, mimicking the action of natural incretin and glucagon hormones. This triple mechanism helps reduce appetite, improve insulin sensitivity, slow gastric emptying and increase energy expenditure and fat oxidation, leading to greater weight loss and metabolic benefits compared with dual agonists.

Researched benefits

Significant and sustained weight loss.
Improved glycemic control and insulin sensitivity.
Increased energy expenditure and fat oxidation.
Potential cardiometabolic benefits.
Improvements in metabolic markers (lipids, liver enzymes, etc.).
Areas of research

Obesity and weight management
Type 2 diabetes and metabolic health
Cardiovascular risk reduction
Non-alcoholic fatty liver disease (NAFLD)
Dyslipidemia and lipid metabolism
Body composition
Energy expenditure and thermogenesis
Important considerations

Common side effects include nausea, vomiting, diarrhea, constipation and abdominal discomfort, especially when starting or increasing the dose.
Requires individual evaluation, especially in people with a history of diabetes, gastrointestinal problems, pancreatitis or endocrine conditions.
Dosing and duration should be personalized based on individual goals and under professional supervision.
May not be appropriate in certain cases (e.g. pregnancy, breastfeeding, history of pancreatitis or medullary thyroid carcinoma).

What to watch for during use

Gradual decrease in body weight.
Lower appetite and a greater feeling of fullness.
Improvement in blood glucose levels and metabolic markers.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Metabolism and weight
Cagrisema

Advanced dual agonist · Metabolism, weight and glucose control
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What is it?
Cagrisema is an experimental dual-action peptide that combines an amylin analogue (cagrilintide) with a GLP-1 agonist (semaglutide). It is being studied for the treatment of obesity and metabolic disorders.

How does it work biologically?
Cagrisema combines two complementary mechanisms: it activates amylin receptors and GLP-1 receptors in the brain and digestive system. This leads to greater appetite reduction, slower gastric emptying, increased satiety and better glucose control, with the potential for greater efficacy than single agonists.

Researched benefits

Significant reduction in body weight.
Better glucose control and insulin resistance.
Greater satiety and lower calorie intake.
Favorable effects on fat metabolism.
Potential benefit on cardiometabolic markers.
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation in people with a medical history, especially diabetes, gastrointestinal problems or pancreatitis.
Dosing and duration should be personalized according to goals and professional supervision.
May not be suitable in certain cases (e.g. pregnancy, breastfeeding, history of medullary thyroid cancer, MEN2 or pancreatitis).

What to watch for during use

Gradual decrease in body weight.
Possible gastrointestinal effects (nausea, constipation, diarrhea), especially at the beginning.
Improvements in blood glucose levels and metabolic markers.
Changes in appetite, satiety and energy levels.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Metabolism and weight
Tesamorelin

Visceral fat reduction and metabolic support
Requires a professional evaluation
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What is it?
Tesamorelin is a growth hormone-releasing hormone (GHRH) analogue that stimulates the natural release of growth hormone (GH) from the pituitary gland. It is FDA-approved to reduce excess abdominal fat in adults with HIV and lipodystrophy, and it has been studied for its potential to improve body composition, metabolism and some cardiometabolic markers.

How does it work biologically?
Tesamorelin binds to GHRH receptors in the pituitary gland, stimulating the pulsatile release of growth hormone (GH), which increases IGF-1 production in the liver and other tissues. This axis may support visceral fat reduction, improve body composition and have positive effects on lipid and carbohydrate metabolism.

Researched benefits

Visceral fat reduction: decrease in excess abdominal fat observed in clinical studies.
Better body composition: increase in lean mass and reduction in total fat.
Metabolic support: may improve markers such as lipids, glucose and insulin sensitivity.
Cardiometabolic health: associated with improvements in some cardiovascular risk markers.
Overall function: support for energy, wellbeing and vitality (according to studies).
Areas of research

Visceral fat
Body composition
Metabolism
Cardiovascular health
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to the goal and individual condition.
Medical history, current medications and risk factors must be considered.

What to watch for during use

Changes in body composition and waist circumference.
Time to see results (several months, depending on the protocol).
Possible side effects such as headache, facial flushing, nausea or fluid retention.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Metabolism and weight
AOD-9604

Fat metabolism and body composition
Requires a professional evaluation
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What is it?
AOD-9604 is a modified fragment of growth hormone (GH), made up of amino acids 176–191, designed to retain the lipolytic effects of GH without its effects on growth. It has been studied for its potential to help mobilize and metabolize fat, support body fat reduction and improve body composition.

How does it work biologically?
AOD-9604 acts on fat metabolism in adipose tissue, supporting lipolysis (mobilization of fatty acids) and the use of these fatty acids as an energy source. Unlike full GH, it has not been associated with significant effects on bone or tissue growth, since it corresponds to a specific fragment of the GH molecule.

Researched benefits

Support for fat reduction: may support the mobilization of body fat and improved body composition.
Muscle preservation: combined with exercise and proper nutrition, it may help preserve lean mass.
Lipid metabolism: studied for its potential to improve fat metabolism and the use of fatty acids.
Body composition: may contribute to a better fat-to-muscle ratio in the context of a healthy lifestyle.
It continues to be studied for its potential in various metabolic and health areas.
Areas of research

Adipose tissue
Body composition
Liver metabolism
Physical performance
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to the goal, individual condition and response.
It is not FDA-approved for weight loss. Its use is mainly for research.

What to watch for during use

Changes in body composition, especially fat reduction.
Response in muscle mass, energy and physical performance.
Results vary depending on the protocol, lifestyle, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Metabolism and weight
MOTS-c

Cellular energy and metabolic health
Requires a professional evaluation
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What is it?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is an endogenous peptide of mitochondrial origin that has shown beneficial effects in preclinical studies on metabolic function, insulin sensitivity, the cellular stress response and mitochondrial health. It is mainly studied for its ability to regulate energy metabolism and promote cellular resilience under metabolic stress.

How does it work biologically?
MOTS-c acts as a metabolic signal produced in the mitochondria that travels into the cell, where it activates pathways related to the regulation of energy metabolism, insulin sensitivity, the cellular stress response and glucose homeostasis. It has been observed to activate the AMPK pathway, influence fatty acid metabolism and help maintain mitochondrial function under stress.

Researched benefits

Improves insulin sensitivity and glucose regulation.
Increases mitochondrial function and energy production (ATP).
Supports lipid metabolism and fat burning in preclinical models.
Supports the cellular stress response and metabolic health.
May improve physical endurance and performance in research models.
Being studied for its possible effects on brain health and cellular longevity.
Areas of research

Mitochondrial function
Glucose metabolism
Lipid metabolism
Brain health and longevity
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
More human research is needed to determine its safety and real clinical benefits.
Current evidence comes mainly from preclinical studies in cell and animal models.

What to watch for during use

Gradual increase in energy and endurance (frequently reported in research).
Better control of glucose and appetite in some cases (according to current evidence).
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.

Recovery and repair

4

Recovery and repair
BPC-157

Tissue recovery and regeneration
Requires a professional evaluation
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What is it?
BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a human gastric protein that has shown strong protective and regenerative effects in various tissues, including tendons, muscles, ligaments, bones, cartilage and the gastrointestinal system.

How does it work biologically?
BPC-157 works by modulating multiple tissue repair and protection pathways. It supports angiogenesis (formation of new blood vessels), reduces inflammation, protects cells from damage and speeds up the healing of tendons, ligaments, muscles, bones and gastrointestinal tissue.

Researched benefits

Speeds up recovery from tendon and ligament injuries.
Supports muscle repair and reduces overuse damage.
Supports bone healing and joint health.
Protects the gastrointestinal lining and may help with ulcers and digestive tract lesions.
Reduces inflammation and pain in different tissues.
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with complex medical conditions or who use anticoagulants.
Dosing and duration should be personalized according to goals and professional supervision.
More human research is still needed, although preclinical evidence is extensive and promising.

What to watch for during use

Improvement in pain, inflammation and mobility in injured areas.
Faster recovery after physical activity or injuries.
Improvement in gastrointestinal symptoms (such as pain, inflammation or discomfort).
Generally good tolerance in most cases.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Recovery and repair
TB-500

Thymosin Beta 4 · Repair and mobility
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What is it?
TB-500 (Thymosin Beta 4) is a synthetic peptide derived from a natural protein found in the human body. It has shown strong effects on tissue repair, reducing inflammation and improving mobility, especially in muscles, tendons, ligaments and connective tissue.

How does it work biologically?
TB-500 mimics the natural action of thymosin beta 4, a key protein in regulating cell movement and tissue repair. It stimulates the migration of repair cells, reduces inflammation, promotes angiogenesis and helps organize tissue during healing, supporting a faster and more functional recovery.

Researched benefits

Speeds up recovery of tendons, ligaments and muscles.
Improves mobility and physical function after injuries.
Reduces inflammation and pain.
Supports regeneration of connective tissue.
Promotes angiogenesis (formation of new blood vessels).
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation in people with complex medical conditions, anticoagulant use or a history of cancer.
Dosing and duration should be personalized according to goals and professional supervision.
More human research is still needed, although preclinical evidence is extensive and promising.

What to watch for during use

Less pain and inflammation in injured areas.
Improved mobility, flexibility and functional strength.
Faster recovery after physical activity or procedures.
Better joint function and quality of movement.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Recovery and repair
Wolverine Blend

BPC-157 + TB-500 · Advanced tissue recovery
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What is it?
The combination of BPC-157 and TB-500, known as the Wolverine Blend, brings together the synergistic effects of these two peptides to boost tissue repair, reduce inflammation and speed up recovery from muscle, tendon, ligament and joint injuries.

How does it work biologically?
The Wolverine Blend combines the action of BPC-157, which protects and regenerates gastrointestinal tissue, tendons, ligaments and muscles, with TB-500, which enhances cell migration, angiogenesis and tissue organization during repair. Together, they offer a more complete, faster and more effective response in injury recovery.

Researched benefits

Faster recovery of tendons, ligaments and muscles.
Less pain and inflammation in acute and chronic injuries.
Better mobility, strength and physical function.
Support for cartilage and connective tissue regeneration.
Potential to shorten post-surgical recovery time.
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation in people with a medical history, especially autoimmune conditions or cancer.
Dosing and duration should be personalized according to goals and professional supervision.
May not be suitable in certain cases (e.g. pregnancy, breastfeeding, anticoagulant use or active disease).

What to watch for during use

Less pain, inflammation and stiffness in the injured area.
Progressive improvement in mobility, strength and function.
Faster recovery after physical activity or procedures.
Greater tolerance to movement and better quality of life.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Recovery and repair
IGF-1 LR3

Cell growth, protein synthesis and muscle recovery
Requires a professional evaluation
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What is it?
IGF-1 LR3 (Insulin-like Growth Factor 1 Long R3) is an IGF-1 analogue with an extended half-life. It is being studied for its potential to promote cell growth, protein synthesis, muscle recovery and tissue regeneration in different systems of the body.

How does it work biologically?
IGF-1 LR3 binds to the IGF-1 receptor on the cell surface, activating signaling pathways such as PI3K/AKT/mTOR, which promote protein synthesis, cell growth and inhibition of muscle breakdown. Its modification at position 3 (arginine) extends its half-life, allowing a more sustained action compared with natural IGF-1.

Researched benefits

Promotes cell growth and protein synthesis.
Supports muscle recovery after exercise.
May support regeneration of tissues such as muscle, tendon and cartilage.
Contributes to maintaining bone mass and mineral density.
Being studied for its potential in repair and recovery processes in different tissues.
Areas of research

Skeletal muscle
Tendon and ligament
Bone health
Tissue regeneration
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to individual goals.
Proper monitoring of the response, body composition and relevant markers is important.

What to watch for during use

Changes in body composition, muscle recovery and physical performance (according to individual goals).
Improvement in strength, endurance and recovery capacity.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.

Skin and beauty

4

Skin and beauty
GHK-Cu

Copper peptide · Regeneration, skin and cell repair
Requires a professional evaluation
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What is it?
GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a peptide naturally present in the human body that binds to copper. It has shown strong effects on tissue regeneration, collagen production, cell repair and inflammation modulation, especially in the skin, hair and connective tissues.

How does it work biologically?
GHK-Cu is a signaling peptide that binds to copper and acts on multiple cellular pathways. It stimulates fibroblasts, increases the production of collagen, elastin and hyaluronic acid, promotes angiogenesis, modulates inflammation and speeds up tissue repair. It also has antioxidant properties and supports the regeneration of skin, hair and other connective tissues.

Researched benefits

Improves skin health, firmness and elasticity.
Stimulates collagen and elastin production.
May support hair growth and reduce hair loss.
Speeds up wound repair and tissue regeneration.
Has antioxidant and anti-inflammatory properties.
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with complex medical conditions or who use anticoagulants.
Dosing and duration should be personalized according to goals and professional supervision.
Although generally well tolerated, more human research is still needed for some specific uses.

What to watch for during use

Improvement in the appearance of the skin (texture, firmness, hydration).
Possible reduction in hair loss and better hair quality.
Faster healing of wounds and injuries.
Good tolerance in most cases.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Skin and beauty
GLOW

GHK-Cu + BPC-157 + TB-500 · Skin regeneration and healthy aging
Requires a professional evaluation
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What is it?
GLOW is a peptide combination (GHK-Cu, BPC-157 and TB-500) designed to boost skin regeneration, stimulate collagen and elastin production, reduce inflammation and speed up tissue repair. It is used to promote healthier, firmer and younger-looking skin.

How does it work biologically?
The peptide combination in GLOW acts on multiple pathways: it stimulates fibroblast activity, increases the production of collagen, elastin and hyaluronic acid, reduces inflammation, improves microcirculation and speeds up the repair of skin damage. This promotes firmer, more elastic, hydrated skin with better texture, while also supporting wound healing and tissue regeneration.

Researched benefits

Improves the appearance of the skin (firmness, elasticity and texture).
Stimulates the production of collagen, elastin and hyaluronic acid.
Supports healing of wounds and tissue damage.
Reduces inflammation and redness of the skin.
Supports healthy aging and more resilient skin.
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation in people with complex medical conditions, anticoagulant use or a history of cancer.
Dosing and duration should be personalized according to goals and professional supervision.
Although generally well tolerated, more human research is needed for aesthetic and long-term uses.

What to watch for during use

Improvement in skin firmness, texture and radiance.
Less redness and better hydration.
Faster healing of wounds, procedures or aesthetic treatments.
Better tolerance to environmental stress and healthier-looking skin over time.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Skin and beauty
KLOW

GHK-Cu + BPC-157 + TB-500 + KPV · Skin, tissue regeneration and gut health
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What is it?
KLOW is a peptide combination designed to support tissue regeneration, skin health, inflammation modulation and cell repair. Its components act on different biological pathways, offering a comprehensive approach to healthier, stronger and more resilient skin, as well as soft tissue recovery. It also offers researched gastrointestinal benefits, mainly through the action of KPV.

How does it work biologically?
KLOW combines the synergistic action of four complementary peptides that act on tissue repair, inflammation modulation, collagen production and skin health. Together, they help improve the structure, elasticity and hydration of the skin, speed up soft tissue recovery and promote an anti-inflammatory environment. In the gut, KPV helps modulate the inflammatory response, while GHK-Cu, BPC-157 and TB-500 contribute to tissue repair and protection of the intestinal lining.

Researched benefits

Improves the appearance of the skin (firmness, texture and elasticity).
Stimulates the production of collagen, elastin and hyaluronic acid.
Speeds up repair of wounds and soft tissue injuries.
Reduces inflammation and oxidative damage in the skin and tissues.
Supports a stronger skin barrier and better hydration.
Reduces intestinal inflammation and strengthens the gut barrier (under research).
Areas of research

Skin rejuvenation
Tissue repair
Connective tissue health
Stronger skin barrier
Colitis and IBD
Irritable bowel syndrome
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with autoimmune diseases, cancer or complex medical conditions.
Human evidence is still limited and more research is needed for specific and long-term uses.

What to watch for during use

Gradual improvement in the quality, firmness and appearance of the skin.
Faster recovery from injuries and less inflammation in the treated area.
Gradual improvement in gastrointestinal symptoms (such as pain, inflammation, diarrhea or discomfort).
Results vary depending on goals, protocol and individual condition.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Skin and beauty
Melanotan II

Skin pigmentation and photoprotection
Requires a professional evaluation
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What is it?
Melanotan II (MT-II) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that binds to melanocortin receptors, mainly MC1R, stimulating melanin production. It has been studied for its ability to increase skin pigmentation, support tanning and potentially offer some photoprotection, as well as other effects related to the melanocortin system.

How does it work biologically?
Melanotan II acts on melanocytes, mainly through the MC1R receptor, stimulating the production of melanin (eumelanin), which darkens the skin. This response may support natural photoprotection against UV radiation. It may also influence areas of the brain related to appetite, sexual function and the stress response, due to its affinity for different melanocortin receptors.

Researched benefits

Increases pigmentation: stimulates melanin production, supporting a darker skin tone.
Natural photoprotection: may help protect the skin from UV damage.
Potential in skin conditions: studied in vitiligo, photodermatoses and other pigmentation disorders.
Other potential effects: may influence appetite, libido and the stress response.
Its potential in various medical areas continues to be studied.
Areas of research

Photoprotection and tanning
Pigmentation disorders
Melanocortin system
Skin health
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to the goal, individual condition and response.
Medical history, current medications and risk factors must be considered, especially a history of skin cancer or pigmented lesions.
It is not approved by regulators for cosmetic or tanning use.

What to watch for during use

Changes in skin pigmentation and response to the sun.
Possible side effects such as nausea, facial flushing, increased appetite and changes in libido.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.

Immunity and gut health

2

Immunity and gut health
KPV

Inflammation, gut health and immune modulation
Requires a professional evaluation
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What is it?
KPV (Lysine-Proline-Valine) is a synthetic peptide derived from alpha-melanocortin that has shown anti-inflammatory, immune-modulating and gut barrier protective effects in preclinical studies. It is mainly being studied for its ability to reduce inflammation in the gastrointestinal tract and in other inflammatory conditions.

How does it work biologically?
KPV acts as an agonist of melanocortin receptors, which helps modulate the inflammatory response, strengthen the intestinal barrier and promote repair of the intestinal lining. Its effects are mainly due to lower production of pro-inflammatory cytokines, improved integrity of tight junctions and regulation of immune cell activity.

Researched benefits

Reduces intestinal inflammation and gastrointestinal symptoms.
Strengthens the intestinal barrier and reduces permeability.
Modulates the immune response and supports an anti-inflammatory environment.
May be useful in conditions such as colitis, Crohn's disease and IBS (under research).
It is also being studied in inflammatory conditions of the skin and other tissues.
Areas of research

Gut health
Irritable bowel syndrome
Skin conditions
Systemic inflammatory conditions
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with complex gastrointestinal or autoimmune conditions.
Although the evidence is promising, more human research is needed for some specific uses.

What to watch for during use

Improvement in gastrointestinal symptoms (such as pain, inflammation, diarrhea or discomfort).
Better tolerance to food and improved digestive function.
Good tolerance in most cases (according to current evidence).
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Immunity and gut health
Thymosin Alpha-1

Immune regulation and antiviral response
Requires a professional evaluation
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What is it?
Thymosin Alpha 1 (TA1) is an endogenous 28-amino-acid peptide naturally found in the thymus. It has been widely studied for its ability to modulate the immune system, especially the maturation and activity of T lymphocytes. In preclinical and clinical studies, TA1 has shown potential benefits for the immune response, defense against viral infections, inflammation modulation and support in conditions of immune dysfunction.

How does it work biologically?
Thymosin Alpha 1 acts as an immunomodulator that influences the differentiation, maturation and activity of T lymphocytes. It may increase cytokine production, improve the function of NK (natural killer) and dendritic cells, and support a more balanced immune response. It has also been studied for its ability to modulate inflammation, reduce viral replication and improve the immune response in immunosuppressed conditions.

Researched benefits

Supports the immune response against viral infections.
Stimulates the activity and maturation of T lymphocytes (CD4+ and CD8+).
May improve the function of NK and dendritic cells.
Helps modulate inflammation and balance the immune response.
Being studied for its potential in immunosuppression and immune recovery.
Areas of research

Viral infections
Immune function
Inflammation modulation
Respiratory health
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in immunosuppressed people or those with complex medical conditions.
Current evidence comes mainly from preclinical and specific clinical studies, and more research on long-term safety is needed.

What to watch for during use

Changes in the immune response and frequency of infections (according to current evidence).
Possible reduction in inflammation and improvement in overall wellbeing.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.

Cognition, stress and sleep

4

Cognition, stress and sleep
Selank

Anxiety, mood and cognitive function
Requires a professional evaluation
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What is it?
Selank is a synthetic peptide developed in Russia with anxiolytic, nootropic and immune-modulating properties. It acts on neurotransmitter systems such as GABA, serotonin and dopamine, helping to reduce anxiety and improve mood, concentration and stress resilience. It is being studied for its potential to promote emotional balance and cognitive function without significant sedative effects.

How does it work biologically?
Selank acts as a modulator of neurotransmitter systems, mainly GABA, serotonin and dopamine. It influences the expression of neurotrophic factors such as BDNF, promotes synaptic plasticity and helps normalize the stress response. It is also being studied for its ability to modulate immune function and reduce inflammation in the central nervous system.

Researched benefits

Reduced anxiety and worry.
Better mood and emotional wellbeing.
Increased concentration, memory and mental focus.
May support stress resilience and emotional stability.
Being studied for its neuroprotective effects and its potential for neuroplasticity.
Areas of research

Anxiety disorders
Cognitive function
Neuroprotection
Immune function
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with psychiatric conditions or who use medications for anxiety, depression or neurological disorders.
Human evidence is still limited and more research is needed for specific uses and long-term safety.

What to watch for during use

Gradual improvement in anxiety, mood and mental clarity (according to current evidence).
May help with better stress management and greater tolerance to challenging situations.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Cognition, stress and sleep
Semax

Cognitive function and neuroprotection
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What is it?
Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH) that has shown promising effects on cognitive function, neuroprotection and neuroplasticity in preclinical and clinical studies. It is mainly studied for its ability to improve memory, attention and stress resilience, as well as its potential to protect neurons and support neurological recovery.

How does it work biologically?
Semax acts as an ACTH analogue and binds to receptors in the brain, modulating the activity of several neurotransmitter systems such as dopamine, serotonin, GABA and glutamate. It influences neurotrophic factors such as BDNF (brain-derived neurotrophic factor), which may promote neuroplasticity, neuron survival and the formation of new synapses. It is also being studied for its ability to improve cerebral circulation and reduce oxidative stress in nervous tissue.

Researched benefits

Improves memory, attention and learning.
May increase concentration and mental focus.
Supports neuroplasticity and the formation of new neural connections.
Potential neuroprotective effect in conditions of neuronal damage (under research).
May help reduce anxiety and improve the stress response.
Being studied for its potential in neurological disorders and cognitive recovery (under research).
Areas of research

Cognitive function
Neuroprotection
Neuroplasticity
Cerebral circulation
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with neurological or psychiatric conditions or who take medications.
Human evidence is limited and more research is needed for specific uses and long-term safety.

What to watch for during use

Gradual improvement in attention, memory and focus (according to current evidence).
Less anxiety and better stress tolerance.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Cognition, stress and sleep
DSIP

Sleep, neurophysiological balance and stress management
Requires a professional evaluation
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What is it?
DSIP (Delta Sleep-Inducing Peptide) is an endogenous peptide naturally produced in the brain that has been studied for its effects on sleep, nervous system regulation and the stress response. In preclinical studies, DSIP has shown properties that support deeper, more restorative sleep, as well as anxiolytic, immune-modulating and neuroprotective effects.

How does it work biologically?
DSIP acts on the central nervous system, modulating the activity of several neurotransmitters, including GABA, serotonin, dopamine and acetylcholine. It has been observed to influence GABAergic receptors, promoting relaxation and making it easier to fall and stay asleep. It may also modulate the stress response at the level of the hypothalamic-pituitary-adrenal (HPA) axis and has potential anti-inflammatory and immune-modulating effects.

Researched benefits

May improve sleep quality and support deeper sleep.
Helps reduce anxiety and nervous tension.
Promotes relaxation and nervous system balance.
Being studied for its immune-modulating and anti-inflammatory effects.
May have neuroprotective effects and support long-term brain health (under research).
Areas of research

Sleep and sleep cycles
Anxiety and stress
Neuroprotection
Immune function
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with sleep disorders, anxiety, depression or who use psychotropic medications.
Human evidence is still limited and more research on safety and duration of use is needed.

What to watch for during use

Gradual improvement in sleep quality (falling asleep faster, deeper sleep and fewer awakenings).
Less anxiety and a greater sense of calm during the day.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Cognition, stress and sleep
Pinealon

Neuroprotection, brain aging and neuronal health
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What is it?
Pinealon is a synthetic three-amino-acid peptide (Glu-Asp-Arg) that has been studied for its potential to protect neurons, reduce oxidative stress, support healthy brain aging and modulate pineal gland function. It may contribute to better cognitive function, mental clarity and regulation of the sleep-wake cycle.

How does it work biologically?
Pinealon acts on the central nervous system and the pineal gland, where it may influence the production of melatonin, a key regulator of the circadian rhythm. It has also been studied for its ability to protect neurons from oxidative stress, modulate gene expression related to cellular aging and support communication between neurons, supporting better cognitive function and brain health.

Researched benefits

May support neuronal health and cognitive function.
Antioxidant properties that may help protect neurons from oxidative stress.
May support circadian rhythm regulation and sleep quality.
May contribute to healthy brain aging and preservation of neuronal function.
May support natural melatonin production and pineal gland function.
Areas of research

Pineal gland
Neuroprotection
Cognitive function
Circadian rhythm
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to individual goals.
Proper monitoring of the response and overall wellbeing is important.

What to watch for during use

Better sleep quality, mental clarity and concentration.
Greater sense of wellbeing, calm and emotional stability.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.

Vitality, longevity and hormones

5

Vitality, longevity and hormones
CJC-1295 + Ipamorelin

Growth hormone stimulation and muscle recovery
Requires a professional evaluation
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What is it?
CJC-1295 and Ipamorelin are peptides that work in synergy to stimulate the pulsatile release of growth hormone (GH) from the pituitary gland. CJC-1295 acts as a GHRH (growth hormone-releasing hormone) analogue and Ipamorelin acts as a selective ghrelin receptor (GHS-R) agonist, promoting a more physiological and sustained release of GH.

How does it work biologically?
CJC-1295 binds to GHRH receptors in the pituitary gland, increasing the release of growth hormone (GH). Ipamorelin binds to ghrelin receptors (GHS-R), selectively stimulating GH secretion. Together, they act in a complementary way to increase the pulsatile and sustained release of GH, which supports liver production of IGF-1 and activates growth, repair and recovery processes in different tissues of the body.

Researched benefits

Increases the release of growth hormone (GH).
May support muscle recovery and physical performance.
Supports bone health and mineral density, body composition and strength.
Contributes to tissue repair and recovery after exercise.
GH release happens mainly during sleep, supporting natural recovery processes.
Areas of research

Muscle recovery
Bone health
Body composition
Tissue repair
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to individual goals.
Proper monitoring of the response and overall wellbeing is important.

What to watch for during use

Gradual improvement in recovery, body composition and performance (according to individual goals).
Greater sense of energy, wellbeing and sleep quality.
Changes in strength, endurance and physical appearance over time.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Vitality, longevity and hormones
Sermorelin

Natural stimulation of growth hormone
Requires a professional evaluation
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What is it?
Sermorelin is a growth hormone-releasing hormone (GHRH) analogue that stimulates the natural, pulsatile release of growth hormone (GH) from the pituitary gland. It has been studied for its potential to improve body composition, sleep, recovery, bone density and overall wellbeing, especially in people with low GH levels associated with aging.

How does it work biologically?
Sermorelin binds to GHRH receptors in the pituitary gland, stimulating the pulsatile release of growth hormone (GH), which increases IGF-1 production in the liver and other tissues. Unlike synthetic GH, it promotes a more physiological, pulsatile release, helping to maintain the body's natural growth hormone axis.

Researched benefits

Increased lean mass: may support the growth and preservation of muscle mass.
Bone health: studied for its potential for bone density and joint health.
Better sleep: may support deeper, more restorative sleep.
Recovery: may support physical recovery and reduce fatigue.
Overall wellbeing: associated with better energy, vitality and quality of life.
Areas of research

Body composition
Bone and joint health
Sleep and neurological function
Healthy aging
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to the goal, individual condition and response.
Medical history, current medications and risk factors must be considered.

What to watch for during use

Changes in energy, sleep, body composition and overall wellbeing.
Time to see results (weeks to months, depending on the protocol).
Possible side effects such as headache, facial flushing, nausea or tingling at the application site.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Vitality, longevity and hormones
NAD+

Cellular energy, DNA repair and longevity
Requires a professional evaluation
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What is it?
NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme present in every cell of the body. It takes part in hundreds of biochemical reactions, including energy production, DNA repair, regulation of gene expression and mitochondrial function. NAD+ levels decline with age, which has generated great interest in its use for metabolic, cognitive and longevity purposes.

How does it work biologically?
NAD+ acts as a coenzyme that carries electrons in metabolic reactions, especially in energy production inside the mitochondria (Krebs cycle and electron transport chain). It is also a key substrate for enzymes such as sirtuins, PARP and CD38, which regulate DNA repair, gene expression, the cellular stress response and metabolic function. Maintaining optimal NAD+ levels is essential for cell health and function.

Researched benefits

Increases cellular energy production (ATP) and supports mitochondrial function.
Activates DNA repair and maintains genetic integrity.
May support cognitive function, memory and mental clarity (under research).
Supports the cellular stress response and metabolic health.
Being studied for its potential effects on longevity and healthy aging.
Areas of research

Mitochondrial function
DNA repair
Cognitive function
Healthy aging
Important considerations

It does not replace the diagnosis or treatment of a medical condition.
Requires individual evaluation, especially in people with complex medical conditions or who take medications.
Most human evidence is still limited and more research is needed for specific uses and duration of use.

What to watch for during use

Gradual increase in energy and endurance (frequently reported in research).
Better mental focus, cognitive clarity and mood (according to current evidence).
Good tolerance in most cases, although some people may experience effects such as gastrointestinal discomfort.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Vitality, longevity and hormones
Epitalon

Cellular aging, longevity and biological rhythm
Requires a professional evaluation
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What is it?
Epitalon is a synthetic four-amino-acid peptide that is an analogue of epithalamin, a substance naturally produced in the pineal gland. It has been studied for its potential to support the regulation of cellular aging, telomerase activity, telomere health and circadian rhythm regulation.

How does it work biologically?
Epitalon acts at the cellular and neuroendocrine level, influencing the activity of telomerase, an enzyme associated with telomere maintenance. It has also been studied for its effect on gene expression related to cellular aging and for its influence on pineal gland function, which may contribute to better regulation of the circadian rhythm and sleep cycle.

Researched benefits

May support telomerase activity and telomere health.
Antioxidant properties that may help protect cells from oxidative stress.
May support circadian rhythm regulation and sleep quality.
Studied for its potential to modulate gene expression related to cellular aging.
May contribute to overall wellbeing, vitality and healthy longevity.
Areas of research

Telomeres and longevity
Cellular aging
Pineal function and circadian rhythm
Neuroprotection
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to individual goals.
Proper monitoring of the response and overall wellbeing is important.

What to watch for during use

Changes in sleep quality and circadian rhythm regulation.
Greater sense of wellbeing, mental clarity and vitality.
Results vary depending on the protocol, individual condition and duration of use.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.
Vitality, longevity and hormones
PT-141 (Bremelanotide)

Sexual desire and regulation of the sexual response
Requires a professional evaluation
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What is it?
PT-141 (bremelanotide) is an analogue of melanocyte-stimulating hormone (α-MSH) that binds to melanocortin receptors, mainly MC4R, in the central nervous system. It has been studied for its potential to increase sexual desire, improve the sexual response and modulate arousal, acting at the brain level rather than directly on the hormonal system.

How does it work biologically?
PT-141 acts in the brain, where it binds to melanocortin receptors (MC4R) in areas such as the hypothalamus, activating neural pathways associated with desire, motivation and the sexual response. Unlike other treatments, it does not act directly on sex hormones, which may be an advantage in people with normal hormone levels. It has been studied in men and women, including premenopausal and postmenopausal women.

Researched benefits

Increases sexual desire: may help increase sexual interest and motivation.
Improves the sexual response: studied for its potential to improve arousal and satisfaction.
In premenopausal women: FDA-approved for the treatment of hypoactive sexual desire disorder (HSDD).
In postmenopausal women: studied with promising results on desire and sexual response.
In men: may support sexual desire and function, especially when the psychological component is predominant.
Areas of research

Limbic system
Neurotransmitters
Female sexual health
Male sexual function
Important considerations

Requires professional supervision for appropriate use.
The protocol may vary according to the goal, individual condition and response.
Medical history, current medications and risk factors must be considered, especially cardiovascular ones.

What to watch for during use

Changes in sexual desire, arousal and satisfaction.
Time to onset and duration of the effect (depending on the protocol used).
Possible side effects such as nausea, facial flushing, headache and changes in blood pressure.
The information presented is educational. It is not a diagnosis, treatment or personalized medical advice. Any protocol must be evaluated by a health professional.

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The information on this site is educational. Protocols must be evaluated by a health professional. Not all peptides have the same level of evidence, approval or clinical indication.

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